This article is from The Biblical World, Volume 35. View more articles from The Biblical World.View this article on JSTOR.View this article's JSTOR metadata.You may also retrieve all of this items metadata in JSON at the following URL: https://archive.org/metadata/jstor-3141471 Source: http://www.jstor.org/stable/10.2307/3141471
byShearn, Colin T.; Mercer, Kelly E.; Orlicky, David J.; Hennings, Leah; Smathers-McCullough, Rebecca L.; Stiles, Bangyan L.; Ronis, Martin J. J.; Petersen, Dennis R.
This article is from PLoS ONE, volume 9.AbstractBackground: Hepatospecific deletion of PTEN results in constitutive activation of Akt and increased lipogenesis. In mice, the addition of a high fat diet (HFD) downregulates lipogenesis. The aim of this study was to determine the effects of a HFD on hepatocellular damage induced by deletion of PTEN. Methods: 12 Week old male flox/flox hepatospecific PTEN mice (PTENf/f) or Alb-Cre controls were fed a HFD composed of 45% fat-derived calories (from... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018288